What we investigate
Our division conducts clinical studies on skin cancer treatment, dermatologic surgery, local anesthesia, scar treatment, phlebology, diagnosis and treatment of leg ulcers, Martorell hypertensive ischemic leg ulcer and leg compression therapy. We keep an intense cooperation with basic scientists from the SKINTEGRITY.CH network.
KEYWORDS
skin cancer, local anesthesia, leg ulcer, compression therapy, scar
Our research in more detail
Selected publications
SKINTEGRITY.CH Principal Investigators are in bold:
- Vent A, Surber C, Graf Johansen NT, Figueiredo V, Schönbächler G, Imhof L, Buset C and Hafner J (2020). Buffered lidocaine 1%, epinephrine 1:100'000 with sodium bicarbonate (hydrogen carbonate) in a 3:1 ratio is less painful than a 9:1 ratio: A double-blind, randomized, placebo-controlled, crossover trial. J Am Acad Dermatol. 83:159-165.
- Satoh TK, Mellett M, Meier-Schiesser B, Fenini G, Otsuka A, Beer HD, Rordorf T, Maul JT, Hafner J, Navarini AA, Contassot E, French LE (2020). IL36- g drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutivacterium acnes. J Clin Invest 130:1417-1430.
- Rabe E, Partsch H, Morrison N, Meissner MH, Mosti G, Lattimer CR, Carpentier PH, Gaillard S, Jünger M, Urbanek T, Hafner J, Patel M, Wu S, Caprini J, Lurie F, Hirsch T (2020). Risks and contraindications of medical compression treatment - A critical reappraisal. An international consensus statement. Phlebolog, doi: 10.1177/0268355520909066. [Epub ahead of print].
- Pich C, Meylan P, Mastelic-Gavillet B, Nguyen TN, Loyon R, Trang BK, Moser H, Moret C, Goepfert C, Hafner J, Levesque MP, Romero P, Jandus C, and Michalik L (2018). Induction of paracrine signaling in metastatic melanoma cells by PPARγ agonist rosiglitazone activates stromal cells and enhances tumor growth. Cancer Res 78: 6447-6461.
- Hafner J (2016). Calciphylaxis and Martorell hypertensive ischemic leg ulcer: same pattern - one pathophysiology. Dermatology 232: 523-533.